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September 4, 2011 / zzirf

Tricking the body to heal itself with Low-dose naltrexone (LDN)

Low-dose naltrexone (LDN): Tricking the body to heal itself

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) to treat cancer and autoimmune diseases, exerts a profound inhibitory effect on cell proliferation. It has been postulated that opioid receptor blockade by LDN provokes a compensatory elevation in endogenous opioids and opioid receptors that can function after LDN is no longer available. Using a novel tissue culture model of LDN action, the mechanism of LDN has been found to target the opioid growth factor (OGF, [Met5]-enkephalin) and OGF receptor (OGFr) axis. This discovery, reported in the September 2011 issue of Experimental Biology and Medicine, provides new insights into the molecular pathway utilized by an increasingly important clinically prescribed agent that serves as a basic biological regulator of cell proliferative events related to pathobiological states such as cancer and autoimmune diseases.

LDN-X tablets

Prescription Only

 

There is a group on Facebook for people who are taking Low dose Naltrexone (LDN) for Fibromyalgia and (CFS) Fatigue

 

In Australia 4.5mg tablets are available from Oz Pharmacy

website: http://ozpharmacy.com.au

http://ozpharmacy.com.au/index.php?main_page=product_info&cPath=17&products_id=103

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